Oral Consumption of Bread from an RNAi Wheat Line with Strongly Silenced Gliadins Elicits No Immunogenic Response in a Pilot Study with Celiac Disease Patients

Oral Consumption of Bread from an RNAi Wheat Line with Strongly Silenced Gliadins Elicits No Immunogenic Response in a Pilot Study with Celiac Disease Patients

Celiac disease (CD) is a genetically predisposed, T cell-mediated and autoimmune-like disorder caused by dietary exposure to the storage proteins of wheat and related cereals. A gluten-free diet (GFD) is the only treatment available for CD. The celiac immune response mediated by CD4+ T-cells can be...

Full description

Bibliographic Details
Main Authors: María H. Guzmán-López, Susana Sánchez-León, Miriam Marín-Sanz, Isabel Comino, Verónica Segura, Luis Vaquero, Octavio M. Rivero-Lezcano, Jorge Pastor, Carolina Sousa, Santiago Vivas, Francisco Barro
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Nutrients
Subjects:
short-term oral challenge
RNAi wheat
33-mer
gluten-free diet
celiac
E82
Online Access:https://www.mdpi.com/2072-6643/13/12/4548

Internet

https://www.mdpi.com/2072-6643/13/12/4548

Similar Items