Sesamol as a potential small molecule in inhibiting the induction of neurotoxic amyloids fibrils involved in the pathophysiology of alzheimer's disease

The presence of possibly toxic forms of intracellular α-synuclein, binding of aggregated α-synuclein and monomeric Aβ, and the potential co-localization of α-synuclein with intracellular neurofibrillary tangles as well as Aβ plaques in the brain could be the main causes in serious clinical symptoms...

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Bibliographic Details
Main Authors: Hong-Bin Cai, Ming-Ming Li, Tian Ting, Min Yao, Ya-Wen Pan, Rupo Sui
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223004744