RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector
<p>RNA interference (RNAi) is a powerful tool widely used for studying gene function in a number of species. We have previously developed an approach that allows conditional expression of a polymerase III promoter based small hairpin RNA (shRNA) in mice using the Cre-LoxP system. This approach...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2007-01-01
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| Series: | International Journal of Biological Sciences |
| Online Access: | http://www.biolsci.org/v03p0091.htm |