Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism

Although conventional immunohistochemistry for neurotropic rabies virus (RABV) usually shows high preference for neurons, non-neuronal cells are also potential targets, and abortive astrocyte infection is considered a main trigger of innate immunity in the CNS. While in vitro studies indicated diffe...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Madlin Potratz, Luca Zaeck, Michael Christen, Verena te Kamp, Antonia Klein, Tobias Nolden, Conrad M. Freuling, Thomas Müller, Stefan Finke
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2020-02-01
Schriftenreihe:Cells
Schlagworte:
Online Zugang:https://www.mdpi.com/2073-4409/9/2/412