GABA<sub>A</sub> Receptor Benzodiazepine Binding Sites and Motor Impairments in Parkinson’s Disease

GABA<sub>A</sub> Receptor Benzodiazepine Binding Sites and Motor Impairments in Parkinson’s Disease

Flumazenil is an allosteric modulator of the γ-aminobutyric acid-A receptor (GABA<sub>A</sub>R) benzodiazepine binding site that could normalize neuronal signaling and improve motor impairments in Parkinson’s disease (PD). Little is known about how regional GABA<sub>A</sub>R...

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Bibliographic Details
Main Authors: Nicolaas I. Bohnen, Jaimie Barr, Robert Vangel, Stiven Roytman, Rebecca Paalanen, Kirk A. Frey, Peter J. H. Scott, Prabesh Kanel
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Brain Sciences
Subjects:
axial motor impairment
benzodiazepine binding site
dopamine
GABA<sub>A</sub> receptor
Parkinson’s disease
PET
Online Access:https://www.mdpi.com/2076-3425/13/12/1711

Internet

https://www.mdpi.com/2076-3425/13/12/1711

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