New local ganirelix sustained release therapy for uterine leiomyoma. Evaluation in a preclinical organ model

New local ganirelix sustained release therapy for uterine leiomyoma. Evaluation in a preclinical organ model

Currently, there is a limited number of treatment options available for patients with symptomatic leiomyomas, and surgical removal is by far the most frequent procedure. Previous studies found that GnRH agonists and antagonists acting through GnRH receptors led to cell death and decreased extracellu...

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Bibliographic Details
Main Authors: Ana Salas, Patricia García-García, Patricia Díaz-Rodríguez, Carmen Évora, Teresa A. Almeida, Araceli Delgado
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Gonadotropin-releasing hormone (GnRH) antagonists
Leiomyoma
Ganirelix
PLGA-microspheres
Local delivery
Preclinical model
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222012987

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http://www.sciencedirect.com/science/article/pii/S0753332222012987

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