Butyrate inhibits iILC2-mediated lung inflammation via lung-gut axis in chronic obstructive pulmonary disease (COPD)

Abstract Background The study investigated the effects and underlying mechanisms of intestinal flora metabolite butyrate on inflammatory ILC2 cells (iILC2s)-mediated lung inflammation in chronic obstructive pulmonary disease (COPD). Methods Mouse models of COPD and acute exacerbation of COPD (AECOPD...

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Bibliographic Details
Main Authors: Min Jiang, Zhiwei Li, Fengbo Zhang, Zheng Li, Dan Xu, Jing Jing, Fengsen Li, Jing Wang, Jianbing Ding
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-023-02438-z