Heterologous and endogenous U6 snRNA promoters enable CRISPR/Cas9 mediated genome editing in Aspergillus niger

Heterologous and endogenous U6 snRNA promoters enable CRISPR/Cas9 mediated genome editing in Aspergillus niger

Abstract Background U6 promoters have been used for single guide RNA (sgRNA) transcription in the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas9) genome editing system. However, no available U6 promoters have been identified in Aspergillus niger, whi...

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Bibliographic Details
Main Authors: Xiaomei Zheng, Ping Zheng, Jibin Sun, Zhang Kun, Yanhe Ma
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Fungal Biology and Biotechnology
Subjects:
Aspergillus niger
CRISPR/Cas9 system
U6 snRNA promoters
Genome editing
Online Access:http://link.springer.com/article/10.1186/s40694-018-0047-4

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http://link.springer.com/article/10.1186/s40694-018-0047-4

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