Access to cyclopropanes with geminal trifluoromethyl and difluoromethylphosphonate groups

Access to cyclopropanes with geminal trifluoromethyl and difluoromethylphosphonate groups

A synthetic route to the bench-stable fluorinated masked carbene reagent diethyl 2-diazo-1,1,3,3,3-pentafluoropropylphosphonate, bearing a trifluoromethyl and a difluoromethyl group is reported for the first time. Its application in CuI-catalyzed cyclopropanation reactions with aromatic and aliphati...

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Bibliographic Details
Main Authors: Ita Hajdin, Romana Pajkert, Mira Keßler, Jianlin Han, Haibo Mei, Gerd-Volker Röschenthaler
Format: Article
Language:English
Published: Beilstein-Institut 2023-04-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
alkenes
cyclopropanation
diazo compounds
difluoromethylphosphonate
dft calculations
Online Access:https://doi.org/10.3762/bjoc.19.39

Internet

https://doi.org/10.3762/bjoc.19.39

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