DNA methylation-environment interactions in the human genome

Previously, we showed that a massively parallel reporter assay, mSTARR-seq, could be used to simultaneously test for both enhancer-like activity and DNA methylation-dependent enhancer activity for millions of loci in a single experiment (Lea et al., 2018). Here, we apply mSTARR-seq to query nearly t...

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Bibliographic Details
Main Authors: Rachel A Johnston, Katherine A Aracena, Luis B Barreiro, Amanda J Lea, Jenny Tung
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/89371