Prophylactic Administration of Fucoidan Represses Cancer Metastasis by Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs) in Lewis Tumor-Bearing Mice

Prophylactic Administration of Fucoidan Represses Cancer Metastasis by Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs) in Lewis Tumor-Bearing Mice

Fucoidan, a heparin-like sulfated polysaccharide, is rich in brown algae. It has a wide assortment of protective activities against cancer, for example, induction of hepatocellular carcinoma senescence, induction of human breast and colon carcinoma apoptosis, and impediment of lung cancer cells migr...

Full description

Bibliographic Details
Main Authors: Tse-Hung Huang, Yi-Han Chiu, Yi-Lin Chan, Ya-Huang Chiu, Hang Wang, Kuo-Chin Huang, Tsung-Lin Li, Kuang-Hung Hsu, Chang-Jer Wu
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Marine Drugs
Subjects:
fucoidan
sulfated polysaccharide
lung carcinoma
metastasis
cachexia
chemo-preventative agent
Online Access:http://www.mdpi.com/1660-3397/13/4/1882

Internet

http://www.mdpi.com/1660-3397/13/4/1882

Similar Items