Pentamers not found in the universal proteome can enhance antigen specific immune responses and adjuvant vaccines.

Certain short peptides do not occur in humans and are rare or non-existent in the universal proteome. Antigens that contain rare amino acid sequences are in general highly immunogenic and may activate different arms of the immune system. We first generated a list of rare, semi-common, and common 5-m...

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Bibliographic Details
Main Authors: Ami Patel, Jessica C Dong, Brett Trost, Jason S Richardson, Sarah Tohme, Shawn Babiuk, Anthony Kusalik, Sam K P Kung, Gary P Kobinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427150?pdf=render