PIK3CA Gene Mutations in HNSCC: Systematic Review and Correlations with HPV Status and Patient Survival

PIK3CA Gene Mutations in HNSCC: Systematic Review and Correlations with HPV Status and Patient Survival

PIK3CA mutations are believed to contribute to the pathogenesis of human papillomavirus (HPV)-associated head and neck squamous cell carcinomas (HNSCC). This study aims to establish the frequency of PIK3CA mutations in a Portuguese HNSCC cohort and to determine their association with the HPV status...

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Bibliographic Details
Main Authors: Daniela Cochicho, Susana Esteves, Miguel Rito, Fernanda Silva, Luís Martins, Pedro Montalvão, Mário Cunha, Miguel Magalhães, Rui M. Gil da Costa, Ana Felix
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
HNSCC
HPV
p16 INK4a
PIK3CA
Online Access:https://www.mdpi.com/2072-6694/14/5/1286

Internet

https://www.mdpi.com/2072-6694/14/5/1286

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