Optimal treatment strategy of cancers with intratumor heterogeneity

Intratumor heterogeneity hinders the success of anti-cancer treatment due to the interaction between different types of cells. To recapitulate the communication of different types of cells, we developed a mathematical model to study the dynamic interaction between normal, drug-sensitive and drug-res...

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Bibliographic Details
Main Authors: Haifeng Zhang, Jinzhi Lei
Format: Article
Language:English
Published: AIMS Press 2022-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2022625?viewType=HTML