A New Function for Amyloid-Like Interactions: Cross-Beta Aggregates of Adhesins form Cell-to-Cell Bonds

Amyloid structures assemble through a repeating type of bonding called “cross-β”, in which identical sequences in many protein molecules form β-sheets that interdigitate through side chain interactions. We review the structural characteristics of such bonds. Single cell force microscopy (SCFM) shows...

Full description

Bibliographic Details
Main Authors: Peter N. Lipke, Marion Mathelié-Guinlet, Albertus Viljoen, Yves F. Dufrêne
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/8/1013