Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

Abstract The extracellular matrix (ECM) plays an important role in cancer progression. It can be divided into the basement membrane (BM) that supports epithelial/endothelial cell behavior and the interstitial matrix (IM) that supports the underlying stromal compartment. The major components of the E...

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Bibliographic Details
Main Authors: Neel I. Nissen, Morten Karsdal, Nicholas Willumsen
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Oncology
Extracellular matrix (ECM)
Collagens
Cancer-associated fibroblasts (CAFs)
Desmoplasia
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s13046-019-1110-6

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http://link.springer.com/article/10.1186/s13046-019-1110-6

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