Archival influenza virus genomes from Europe reveal genomic variability during the 1918 pandemic

For archival pathogens, like pH1N1 Influenza A virus the causative agent of 1918/19 pandemic, only few whole genome sequences exist. Here, Patrono et al. provide one complete and two partial genomes from Germany and find variation in two sites in the nucleoprotein gene in pandemic samples compared t...

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Bibliographic Details
Main Authors: Livia V. Patrono, Bram Vrancken, Matthias Budt, Ariane Düx, Sebastian Lequime, Sengül Boral, M. Thomas P. Gilbert, Jan F. Gogarten, Luisa Hoffmann, David Horst, Kevin Merkel, David Morens, Baptiste Prepoint, Jasmin Schlotterbeck, Verena J. Schuenemann, Marc A. Suchard, Jeffery K. Taubenberger, Luisa Tenkhoff, Christian Urban, Navena Widulin, Eduard Winter, Michael Worobey, Thomas Schnalke, Thorsten Wolff, Philippe Lemey, Sébastien Calvignac-Spencer
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29614-9