Estetrol Increases Progesterone Genetic Response without Triggering Common Estrogenic Effects in Endometriotic Cell Lines and Primary Cultures

Estetrol (E4), a natural estrogen produced by the human fetal liver, is actively studied for menopause and breast cancer treatment. It has low side effects and preferential estrogen receptor alpha (ER<i>α</i>) affinity. There are no data about its effects on endometriosis, a common gynec...

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Bibliographic Details
Main Authors: Daniel Patiño-García, Jaime Palomino, Cristián Pomés, Claudia Celle, Verónica Torres-Estay, Renán Orellana
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/4/1169