Finasteride Enhances the Generation of Human Myeloid-Derived Suppressor Cells by Up-Regulating the COX2/PGE2 Pathway.

Myeloid-derived suppressor cells (MDSCs) have been known to be a key factor in the regulation of the immune system under numerous conditions such as tumors, infections, autoimmune diseases, and transplantations. In contrast to the proposed deleterious role of MDSCs in tumors and infections, MDSCs wi...

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Bibliographic Details
Main Authors: Shaoying Zhang, Kang Wu, Yufeng Liu, Yingtong Lin, Xu Zhang, Jie Zhou, Hui Zhang, Ting Pan, Yongshui Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4890941?pdf=render