Safety of long-term intrathecal methotrexate in progressive forms of MS

Background: There are few treatment options for multiple sclerosis (MS) patients with advanced disability [expanded disability status scale (EDSS) ⩾ 6.0]. In 2010, we reported initial results of using intrathecal methotrexate (ITMTX) in patients with progressive MS. We now report on long-term use of...

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Bibliographic Details
Main Authors: James W. Stark, Lena Josephs, Deirdre Dulak, Madison Clague, Saud A. Sadiq
Format: Article
Language:English
Published: SAGE Publishing 2019-12-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756286419892360