Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance

<p>Abstract</p> <p>Morphine is widely used to treat chronic pain, however its utility is hindered by the development of tolerance to its analgesic effects. While N-methyl-D-aspartate (NMDA) receptors are known to play roles in morphine tolerance and dependence, less is known about...

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Bibliographic Details
Main Authors: Ko Shanelle W, Wu Long-Jun, Shum Fanny, Quan Jessica, Zhuo Min
Format: Article
Language:English
Published: BMC 2008-06-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/1/1/2