Cingulate NMDA NR2B receptors contribute to morphine-induced analgesic tolerance
<p>Abstract</p> <p>Morphine is widely used to treat chronic pain, however its utility is hindered by the development of tolerance to its analgesic effects. While N-methyl-D-aspartate (NMDA) receptors are known to play roles in morphine tolerance and dependence, less is known about...
Main Authors: | Ko Shanelle W, Wu Long-Jun, Shum Fanny, Quan Jessica, Zhuo Min |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-06-01
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Series: | Molecular Brain |
Online Access: | http://www.molecularbrain.com/content/1/1/2 |
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