Synthesis, Antimicrobial, and Anti-inflammatory Activities of Novel 5-(1-Adamantyl)-4-arylideneamino-3-mercapto-1,2,4-triazoles and Related Derivatives

Synthesis, Antimicrobial, and Anti-inflammatory Activities of Novel 5-(1-Adamantyl)-4-arylideneamino-3-mercapto-1,2,4-triazoles and Related Derivatives

The reaction of 5-(1-adamantyl)-4-amino-3-mercapto-1,2,4-triazole (5) with various aromatic aldehydes in ethanol or acetic acid yielded the corresponding 4-arylideneamino derivatives 6a–v. Treatment of the 4-(2,6-difluoro- and dichlorobenzylideneamino) derivatives 6o and 6q with 1-substituted pipera...

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Bibliographic Details
Main Authors: Mohamed A. Al-Omar, Ebtehal S. Al-Abdullah, Ihsan A. Shehata, Elsayed E. Habib, Tarek M. Ibrahim, Ali A. El-Emam
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Molecules
Subjects:
1-adamantyl derivatives
1,2,4-triazoles
antimicrobial activity
anti-inflammatory activity
Online Access:http://www.mdpi.com/1420-3049/15/4/2526/

Internet

http://www.mdpi.com/1420-3049/15/4/2526/

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