Targeting the alpha subunit of IL-3 receptor (CD123) in patients with acute leukemia

The IL-3 alpha chain receptor (CD123) is a cell surface protein that is widely expressed by various subtypes of acute leukemia, including acute myeloid leukemia (AML), acute lymphoblastic leukemia and blastic plasmacytoid dendritic cell neoplasm. Notably, CD123 is preferentially overexpressed in leu...

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Bibliographic Details
Main Authors: Ibrahim Aldoss, Mary Clark, Joo Y Song, Vinod Pullarkat
Format: Article
Language:English
Published: Taylor & Francis Group 2020-10-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2020.1788299