Targeting the alpha subunit of IL-3 receptor (CD123) in patients with acute leukemia

Targeting the alpha subunit of IL-3 receptor (CD123) in patients with acute leukemia

The IL-3 alpha chain receptor (CD123) is a cell surface protein that is widely expressed by various subtypes of acute leukemia, including acute myeloid leukemia (AML), acute lymphoblastic leukemia and blastic plasmacytoid dendritic cell neoplasm. Notably, CD123 is preferentially overexpressed in leu...

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Detalles Bibliográficos
Main Authors: Ibrahim Aldoss, Mary Clark, Joo Y Song, Vinod Pullarkat
Formato: Artigo
Idioma:English
Publicado: Taylor & Francis Group 2020-10-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
cd123
il3
flotetuzumab
bispecific antibody
tagraxofusp
aml
all
bpdcn
Acceso en liña:http://dx.doi.org/10.1080/21645515.2020.1788299

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