Structural Requirements for the Binding of a Peptide to Prohibitins on the Cell Surface of Monocytes/Macrophages

Structural Requirements for the Binding of a Peptide to Prohibitins on the Cell Surface of Monocytes/Macrophages

The screening of phage peptide libraries resulted in the identification of a sequence (named NW peptide, NWYLPWLGTNDW) that specifically binds to human monocytes and macrophages. Although the NW peptide can be used for the targeted delivery of therapeutics without knowledge of its receptor(s), the i...

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Bibliographic Details
Main Authors: Qindong Zhang, Anniken Olberg, Mouldy Sioud
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
peptides
macrophages
targeted delivery
prohibitins
tumor microenvironment
phage display
Online Access:https://www.mdpi.com/1422-0067/23/8/4282

Internet

https://www.mdpi.com/1422-0067/23/8/4282

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