Curcumin Inhibits α-Synuclein Aggregation by Acting on Liquid–Liquid Phase Transition

Curcumin Inhibits α-Synuclein Aggregation by Acting on Liquid–Liquid Phase Transition

Parkinson’s disease (PD), the second most common neurodegenerative disorder, is linked to α-synuclein (α-Syn) aggregation. Despite no specific drug being available for its treatment, curcumin, from the spice turmeric, shows promise. However, its application in PD is limited by a lack of understandin...

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Bibliographic Details
Main Authors: Jian-Feng Li, Zi-Qun Jiang, Sen Cao, Meng-Xin Zhang, Li-Hui Wang, Jun Liu, Yan-Hua Lu, Hong-Yan Wang, Xiao-Jing Hong, Zhi-Guo Wang, Jun-Ping Liu
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Foods
Subjects:
Parkinson’s disease
α-synuclein
curcumin
anti-aggregation
molecular dynamics
Online Access:https://www.mdpi.com/2304-8158/13/9/1287

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https://www.mdpi.com/2304-8158/13/9/1287

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