Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants

Antifungal Drug Plasma Exposures: A Possible Contribution of Vitamin D-Related Gene Variants

Vitamin D (VD) seems to influence drug clearance and outcome. Antifungal drugs (AFU) are the most used azoles in clinical practice. In the literature, no data are available concerning VD’s impact on AFU therapy. The aim of this study was to analyze if VD pathway-related polymorphisms may influence v...

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Bibliographic Details
Main Authors: Jessica Cusato, Alice Palermiti, Alessandra Manca, Jacopo Mula, Miriam Antonucci, Amedeo De Nicolò, Sarah Allegra, Silvia De Francia, Francesco Chiara, Giovanni Di Perri, Francesco Giuseppe De Rosa, Andrea Calcagno, Antonio D’Avolio
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Pharmaceuticals
Subjects:
genetics
azoles
pharmacokinetics
<i>VDR</i>
<i>CYP27B1</i>
<i>CYP24A1</i>
Online Access:https://www.mdpi.com/1424-8247/15/5/630

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https://www.mdpi.com/1424-8247/15/5/630

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