Structural Characterization and Interaction with RCA120 of a Highly Sulfated Keratan Sulfate from Blue Shark (Prionace glauca) Cartilage

Structural Characterization and Interaction with RCA120 of a Highly Sulfated Keratan Sulfate from Blue Shark (Prionace glauca) Cartilage

As an important glycosaminoglycan, keratan sulfate (KS) mainly exists in corneal and cartilage, possessing various biological activities. In this study, we purified KS from blue shark (Prionace glauca) cartilage and prepared KS oligosaccharides (KSO) through keratanase II-catalyzed hydrolysis. The s...

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Bibliographic Details
Main Authors: Qinying Li, Guoyun Li, Xiaoliang Zhao, Xindi Shan, Chao Cai, Jing Zhao, Fuming Zhang, Robert J. Linhardt, Guangli Yu
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Marine Drugs
Subjects:
Prionace glauca cartilage
keratan sulfate
structural characterization
NMR spectra
HILIC-FTMS
Ricinus communis agglutinin I
Online Access:http://www.mdpi.com/1660-3397/16/4/128

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http://www.mdpi.com/1660-3397/16/4/128

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