Reversal of neurochemical alterations in the spinal dorsal horn and dorsal root ganglia by Mas-related gene (Mrg) receptors in a rat model of spinal nerve injury

Reversal of neurochemical alterations in the spinal dorsal horn and dorsal root ganglia by Mas-related gene (Mrg) receptors in a rat model of spinal nerve injury

The rodent Mas-related gene (Mrg) receptor subtype C has been demonstrated to inhibit pathological pain. This study investigated the mechanisms underlying the reversal of pain hypersensitivity by the selective MrgC receptor agonist bovine adrenal medulla 8–22 (BAM8–22) in a rat model of L5 spinal ne...

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Bibliographic Details
Main Authors: Dongmei Wang, Yaping Xue, Yanhua Yan, Minjie Lin, Jiajia Yang, Jianzhong Huang, Yanguo Hong
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Neurobiology of Disease
Subjects:
Astrocytes
Central sensitization
Dorsal root ganglion (DRG)
Mas-related gene (Mrg) receptor
Neuropathic pain, Spinal dorsal horn
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611630064X

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http://www.sciencedirect.com/science/article/pii/S096999611630064X

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