Post-translational targeting of Rab35 by the effector IcsB of Shigella determines intracellular bacterial niche formation

Post-translational targeting of Rab35 by the effector IcsB of Shigella determines intracellular bacterial niche formation

Summary: Escape from the bacterial-containing vacuole (BCV) is a key step of Shigella host cell invasion. Rab GTPases subverted to in situ-formed macropinosomes in the vicinity of the BCV have been shown to promote its rupture. The involvement of the BCV itself has remained unclear. We demonstrate t...

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Bibliographic Details
Main Authors: Nora Mellouk, Arthur Lensen, Noelia Lopez-Montero, Magdalena Gil, Camila Valenzuela, Kerstin Klinkert, Gael Moneron, Léa Swistak, David DiGregorio, Arnaud Echard, Jost Enninga
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724003620

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http://www.sciencedirect.com/science/article/pii/S2211124724003620

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