Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors

Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors

The COVID-19 outbreak has rapidly spread on a global scale, affecting the economy and public health systems throughout the world. In recent years, peptide-based therapeutics have been widely studied and developed to treat infectious diseases, including viral infections. Herein, the antiviral effects...

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Bibliographic Details
Main Authors: Marjorie C. L. C. Freire, Gabriela D. Noske, Natália V. Bitencourt, Paulo R. S. Sanches, Norival A. Santos-Filho, Victor O. Gawriljuk, Eduardo P. de Souza, Victor H. R. Nogueira, Mariana O. de Godoy, Aline M. Nakamura, Rafaela S. Fernandes, Andre S. Godoy, Maria A. Juliano, Bianca M. Peres, Cecília G. Barbosa, Carolina B. Moraes, Lucio H. G. Freitas-Junior, Eduardo M. Cilli, Rafael V. C. Guido, Glaucius Oliva
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
COVID-19
SARS-CoV-2
inhibitors
Papain-like protease
peptides
Online Access:https://www.mdpi.com/1420-3049/26/16/4896

Internet

https://www.mdpi.com/1420-3049/26/16/4896

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