Engineered extracellular vesicles carrying let-7a-5p for alleviating inflammation in acute lung injury

Abstract Background Acute lung injury (ALI) is a life-threatening respiratory condition characterized by severe inflammation and lung tissue damage, frequently causing rapid respiratory failure and long-term complications. The microRNA let-7a-5p is involved in the progression of lung injury, inflamm...

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Main Authors: Sin-Yu Chen, Yi-Ling Chen, Po-Chen Li, Tai-Shan Cheng, Yeh-Shiu Chu, Yi-Shan Shen, Hsin-Tung Chen, Wei-Ni Tsai, Chien-Ling Huang, Martin Sieber, Yuan-Chieh Yeh, Hsiao-Sheng Liu, Chi-Ling Chiang, Chih-Hung Chang, Andrew S. Lee, Yen-Han Tseng, Ly James Lee, Hsiu-Jung Liao, Hon-Kan Yip, Chi-Ying F. Huang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-024-01019-4