Single-cell transcriptome analysis reveals stem cell-like subsets in the progression of Waldenström’s macroglobulinemia

Abstract Waldenström’s macroglobulinemia (WM) is an uncommon lymphoproliferative disorder, and the precise cellular landscape and the mechanisms of progression from IgM monoclonal gammopathy of undetermined significance (MGUS) to WM remain unclear. We performed single-cell RNA sequencing of CD19 + a...

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Bibliographic Details
Main Authors: Yu Qiu, Xiao-shuang Wang, Yuan Yao, Yan-min Si, Xue-zhu Wang, Ming-nan Jia, Dao-bin Zhou, Jia Yu, Xin-xin Cao, Jian Li
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Experimental Hematology & Oncology
Online Access:https://doi.org/10.1186/s40164-023-00382-6