Mass spectrometry uncovers intermediates and off-pathway complexes for SNARE complex assembly

Chemical cross-linking and native mass spectrometry aid the thorough investigation of complex formation and multimerisation of synaptic vesicle fusion-mediating SNARE complex, including the role of complexin-1 in its assembly.

Bibliographic Details
Main Authors: Julia Hesselbarth, Carla Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04548-0