'Glocal' robustness analysis and model discrimination for circadian oscillators.
To characterize the behavior and robustness of cellular circuits with many unknown parameters is a major challenge for systems biology. Its difficulty rises exponentially with the number of circuit components. We here propose a novel analysis method to meet this challenge. Our method identifies the...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-10-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2758577?pdf=render |