Improved single-chain transactivators of the Tet-On gene expression system

<p>Abstract</p> <p>Background</p> <p>The Tet-Off (tTA) and Tet-On (rtTA) regulatory systems are widely applied to control gene expression in eukaryotes. Both systems are based on the Tet repressor (TetR) from transposon Tn<it>10</it>, a dimeric DNA-binding p...

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Bibliographic Details
Main Authors: Berkhout Ben, Hillen Wolfgang, Berens Christian, Krueger Christel, Hoppes Rieuwert, Symons Jori, Zhou Xue, Das Atze T
Format: Article
Language:English
Published: BMC 2007-01-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/7/6