Environmental insults: critical triggers for amyotrophic lateral sclerosis

Environmental insults: critical triggers for amyotrophic lateral sclerosis

Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterised by a rapid loss of lower and upper motor neurons. As a complex disease, the ageing process and complicated gene-environment interactions are involved in the majority of cases. Main body Signifi...

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Bibliographic Details
Main Authors: Bing Yu, Roger Pamphlett
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Translational Neurodegeneration
Subjects:
Amyotrophic lateral sclerosis
Environmental risk factors
Mendelian randomisation
Mitochondrial dysfunction
Trigger
Initiation
Online Access:http://link.springer.com/article/10.1186/s40035-017-0087-3

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http://link.springer.com/article/10.1186/s40035-017-0087-3

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