The CaMKII/MLC1 Axis Confers Ca<sup>2+</sup>-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes

The CaMKII/MLC1 Axis Confers Ca<sup>2+</sup>-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes

Astrocytes, the main glial cells of the central nervous system, play a key role in brain volume control due to their intimate contacts with cerebral blood vessels and the expression of a distinctive equipment of proteins involved in solute/water transport. Among these is MLC1, a protein highly expre...

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Bibliographic Details
Main Authors: Maria Stefania Brignone, Angela Lanciotti, Antonio Michelucci, Cinzia Mallozzi, Serena Camerini, Luigi Catacuzzeno, Luigi Sforna, Martino Caramia, Maria Cristina D’Adamo, Marina Ceccarini, Paola Molinari, Pompeo Macioce, Gianfranco Macchia, Tamara Corinna Petrucci, Mauro Pessia, Sergio Visentin, Elena Ambrosini
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
brain edema
astrocytes
Ca<sup>2+</sup> release
ICl,<sub>swell</sub>
VRAC
CaMKII
Online Access:https://www.mdpi.com/2073-4409/11/17/2656

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https://www.mdpi.com/2073-4409/11/17/2656

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