Quantile-specific heritability of mean platelet volume, leukocyte count, and other blood cell phenotypes
Introduction: “Quantile-dependent expressivity” occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g. mean platelet volume, MPV) is high or low relative to its distribution. Methods: Offspring-parent (βOP) regression slopes were estimated by quantile regression,...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2022-09-01
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| Series: | Lifestyle Genomics |
| Online Access: | https://www.karger.com/Article/FullText/527048 |