Optimization of Zika virus envelope protein production for ELISA and correlation of antibody titers with virus neutralization in Mexican patients from an arbovirus endemic region

Optimization of Zika virus envelope protein production for ELISA and correlation of antibody titers with virus neutralization in Mexican patients from an arbovirus endemic region

Abstract Background Zika virus (ZIKV) has become a global threat with immediate need for accurate diagnostics, efficacious vaccines and therapeutics. Several ZIKV envelope (Env)-based vaccines have been developed recently. However, many commercially available ZIKV Env are based on the African lineag...

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Bibliographic Details
Main Authors: Young Chan Kim, Cesar Lopez-Camacho, Joanne E. Nettleship, Nahid Rahman, Michelle L. Hill, Laura Silva-Reyes, Georgina Ortiz-Martinez, Gloria Figueroa-Aguilar, María Antonieta Mar, Héctor Vivanco-Cid, Christine S. Rollier, Nicole Zitzmann, Martha Eva Viveros-Sandoval, Raymond J. Owens, Arturo Reyes-Sandoval
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Virology Journal
Subjects:
Zika virus
Envelope protein
CD4 fusion tag
Protein production
ELISA
Mexican patients
Online Access:http://link.springer.com/article/10.1186/s12985-018-1104-6

Internet

http://link.springer.com/article/10.1186/s12985-018-1104-6

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