A New N-Substituted 1<i>H</i>-Isoindole-1,3(2<i>H</i>)-Dione Derivative—Synthesis, Structure and Affinity for Cyclooxygenase Based on In Vitro Studies and Molecular Docking
Isoindoline-1,3-dione derivatives constitute an important group of medicinal substances. In this study, nine new 1<i>H</i>-isoindole-1,3(2<i>H</i>)-dione derivatives and five potential pharmacophores were obtained in good yield (47.24–92.91%). The structure of the new imides...
Main Authors: | Dominika Szkatuła, Edward Krzyżak, Paulina Stanowska, Magdalena Duda, Benita Wiatrak |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/14/7678 |
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