Polygenic risk scores: from research tools to clinical instruments

Polygenic risk scores: from research tools to clinical instruments

Abstract Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have enabled researchers to identify genetic variants associated with diseases. These variants can be combined into a polygenic risk score that captures part of a...

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Bibliographic Details
Main Authors: Cathryn M. Lewis, Evangelos Vassos
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Genome Medicine
Subjects:
Genetics
Common disorders
Polygenic risk scores
Prediction
Pharmacogenetics
Risk
Online Access:http://link.springer.com/article/10.1186/s13073-020-00742-5

Internet

http://link.springer.com/article/10.1186/s13073-020-00742-5

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