Anticodon Wobble Uridine Modification by Elongator at the Crossroad of Cell Signaling, Differentiation, and Diseases

First identified 20 years ago as an RNA polymerase II-associated putative histone acetyltransferase, the conserved Elongator complex has since been recognized as the central player of a complex, regulated, and biologically relevant epitranscriptomic pathway targeting the wobble uridine of some tRNAs...

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Bibliographic Details
Main Author: Damien Hermand
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/4/2/7