Anticodon Wobble Uridine Modification by Elongator at the Crossroad of Cell Signaling, Differentiation, and Diseases
First identified 20 years ago as an RNA polymerase II-associated putative histone acetyltransferase, the conserved Elongator complex has since been recognized as the central player of a complex, regulated, and biologically relevant epitranscriptomic pathway targeting the wobble uridine of some tRNAs...
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Format: | Article |
Language: | English |
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MDPI AG
2020-05-01
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Series: | Epigenomes |
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Online Access: | https://www.mdpi.com/2075-4655/4/2/7 |