The role of RICTOR amplification in targeted therapy and drug resistance

Abstract The emergence of tyrosine kinase inhibitors (TKIs) has changed the current treatment paradigm and achieved good results in recent decades. However, an increasing number of studies have indicated that the complex network of receptor tyrosine kinase (RTK) co-activation could influence the cha...

Full description

Bibliographic Details
Main Authors: Deze Zhao, Man Jiang, Xiaochun Zhang, Helei Hou
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-020-0146-6