The role of RICTOR amplification in targeted therapy and drug resistance
Abstract The emergence of tyrosine kinase inhibitors (TKIs) has changed the current treatment paradigm and achieved good results in recent decades. However, an increasing number of studies have indicated that the complex network of receptor tyrosine kinase (RTK) co-activation could influence the cha...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s10020-020-0146-6 |