Stochastic model of vesicular stomatitis virus replication reveals mutational effects on virion production.

We present the first complete stochastic model of vesicular stomatitis virus (VSV) intracellular replication. Previous models developed to capture VSV's intracellular replication have either been ODE-based or have not represented the complete replicative cycle, limiting our ability to understan...

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Bibliographic Details
Main Authors: Connor R King, Casey-Tyler Berezin, Jean Peccoud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-02-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011373&type=printable