Tumor-derived small extracellular vesicles promote breast cancer progression by upregulating PD-L1 expression in macrophages

Tumor-derived small extracellular vesicles promote breast cancer progression by upregulating PD-L1 expression in macrophages

Abstract Background The metastasis of breast cancer (BC) is a complex multi-step pathological process, strictly dependent on the intrinsic characteristics of BC cells and promoted by a predisposing microenvironment. Although immunotherapy has made important progress in metastasis BC, the heterogenei...

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Bibliographic Details
Main Authors: Di Xu, Wen-Quan Chen, Ming-Xing Liang, Xiu Chen, Zhen Liu, Yin-Jiao Fei, Xin-Yi Shao, Yang Wu, Wei Zhang, Jin-Hai Tang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Cancer Cell International
Subjects:
Breast cancer
Macrophages
Small extracellular vesicles
PD-L1
MicroRNA
Online Access:https://doi.org/10.1186/s12935-023-02980-0

Internet

https://doi.org/10.1186/s12935-023-02980-0

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