Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference

Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference

Novel highly pathogenic avian influenza (HPAI) H5Nx viruses are predominantly circulating worldwide, with an increasing potential threat of an outbreak in humans. It remains largely unknown how the stably maintained HPAI H5N1 suddenly altered its neuraminidase (NA) to other NA subtypes, which result...

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Bibliographic Details
Main Authors: Khristine Joy C. Antigua, Yun Hee Baek, Won-Suk Choi, Ju Hwan Jeong, Eun-Ha Kim, Sol Oh, Sun-Woo Yoon, Changil Kim, Eung-Gook Kim, So-Young Choi, Seung Kon Hong, Young Ki Choi, Min Suk Song
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
Avian influenza
clade 2.3.4
H5Nx
antigenic drift
antigenic shift
functional balance
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2022.2082672

Internet

https://www.tandfonline.com/doi/10.1080/21505594.2022.2082672

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