Improvement of physicochemical parameters of acyclovir using cocrystallization approach
ABSTRACT Acyclovir is an antiviral drug having potent activity against the virus of herpes family and varicella zoster. Unfortunately, drug suffers very poor oral bioavailability (15-30%). The main objective of present study was to develop acyclovir cocrystals with improved solubility which may resu...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Universidade de São Paulo
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Series: | Brazilian Journal of Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000400727&lng=en&tlng=en |