Mutations changing tropomodulin affinity for tropomyosin alter neurite formation and extension
Assembly of the actin cytoskeleton is an important part of formation of neurites in developing neurons. Tropomodulin, a tropomyosin-dependent capping protein for the pointed end of the actin filament, is one of the key players in this process. Tropomodulin binds tropomyosin in two binding sites. Tmo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2013-02-01
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| Series: | PeerJ |
| Subjects: | |
| Online Access: | https://peerj.com/articles/7.pdf |